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Tobb says the only way to identify a PAM gene variant is through genetic testing, since there are no symptoms or routine lab tests that can detect it
This is especially significant because the pharmaceutical industry is currently shifting gears
It acts through the GLP-1 receptor (GLP-1R), a G protein-coupled receptor (GPCR) predominantly expressed in pancreatic -cells, the gastrointestinal tract, and the central nervous system
Recombinant HEK293 cells stably expressing GLP-1R and controlled by the cAMP expression of the firefly luciferase gene are used
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