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10.1016/j.phymed.2021.153755 204 JayawardenaR.RanasingheP.RanawakaH.GamageN.DissanayakeD.MisraA
The fundamental cause of DOX-induced ovarian failure is known to be increased formation of reactive oxygen species (ROS), and many free radical scavengers have been studied to prevent POI 78
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However, muscle mass does not appear to recover when the drug is stopped and is of potential concern especially for older patients though its impact on overall health is unclear (1)
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