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Month Three: Consolidated Results and Pattern Recognition By the 12-week mark, total weight loss typically ranges from 8 to 18 pounds for most patients, though responses vary significantly based on starting weight, metabolism, and genetic factors like variants in GLP1R and FTO genes that influence semaglutide effectiveness
Conclusion: Semaglutide reduces the risk of AF, complete AV block, death from CV causes, and revascularization in patients with T2D, with long-term treatment showing greater benefits for arrhythmic outcomes
npj Syst Biol Appl 11 , 144 (2025)