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76 Several studies have shown that the presence of antioxidants in a variety of plants, including lycopene, retinol, - and -tocopherol, -cryptoxanthin, - and -carotene, lutein, and zeaxanthin, significantly lowers the risk of diabetes complications

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The AAFP advises that injectable therapy leads to more rapid improvement and should be considered in patients with severe deficiency or severe neurologic symptoms (Langan RC, Goodbred AJ, 2017)

Diabetic retinopathy complications have been observed in some patients with pre-existing retinopathy who experience rapid improvements in glycemic control with semaglutide therapy