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8 Weight regain is a common reality upon cessation of these medications if underlying lifestyle patterns have not shifted

(2025) 'Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial' [Accessed 19 Jan

5, 6-dioxyuracil) was purchased from Sigma-Aldrich (St

Semaglutide has been marketed for over a decade in diabetes care, and SELECT outcomes data extends beyond five years

Younger patients who achieve substantial weight loss and demonstrate capacity for sustained dietary and exercise changes may be candidates for medication discontinuation with close monitoring