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Renal (kidney) function : According to the UK SmPC, no dose adjustment is required for patients with renal impairment, including those with severe kidney disease

As we delve further into semaglutides role in the management of diabetes and obesity, the balance between its benefits and risks remains a focal point of discussion among healthcare providers and researchers alike

doi:10.2337/dc24-S004 Watanabe JH, Kwon J, Nan B, Reikes A

& Alachkar, A

Moreover, excessive fission disrupts mitochondrial membrane potential, causes mitochondrial damage, and impairs both cellular energy metabolism and iron homeostasis, further sensitizing cells to ferroptosis [56]