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doi: 10.1097/XCE.0000000000000321 76 ProchzkovNLaursenMFLa BarberaGTsekitsidiEJrgensenMSRasmussenMAet al

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Cancer cells may metabolize glutamate to -ketoglutarate through one of two different pathways (glutamate dehydrogenase or aminotransferases), with aminotransferases potentially supporting a more biosynthetic and pro-growth phenotype