Studies have shown that extracellular vesicles derived from the endometrium and the miRNAs they carry can influence cellular EMT, which is closely related to the occurrence and progression of RM, affecting pregnancy outcomes (Li et al., 2018)
Providing your system with a high-quality antioxidant during this window can support the natural "clean-up" processes that happen overnight
Common causes: MTHFR gene mutations (C677T, A1298C) reducing enzyme efficiency Vitamin B deficiencies (folate, B12, B6) preventing homocysteine recycling Kidney disease impairing homocysteine clearance Certain medications (methotrexate, antacids, metformin) Hypothyroidism Aging Health risks associated with high homocysteine: Cardiovascular disease damages blood vessel walls, promotes atherosclerosis Blood clots increases risk of DVT, pulmonary embolism, stroke Heart attack and stroke particularly when levels exceed 15 mol/L Pregnancy complications miscarriage, preeclampsia, neural tube defects Cognitive decline Alzheimers disease, dementia, memory problems Osteoporosis weakens bone structure Depression and mental health issues Treatment approach: Increase methylated B vitamins (methylfolate, methyl-B12, B6) Improve diet with folate-rich foods Address underlying deficiencies Support methylation pathways Monitor and reduce levels to optimal range (below 10 mol/L) The goal: Lower homocysteine by improving your bodys ability to process it efficiently
Another serious complication associated with the use of KD involves potential changes in the lipid profile, particularly an increase in low-density lipoprotein (LDL) cholesterol (231, 233)
These medications should be used with caution in people with severe gastrointestinal disease, including severe gastroparesis
