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Learn where to self-administer a B12 shot and how to do it painlessly This article was medically reviewed by Shari Forschen, NP, MA and by wikiHow staff writer, Amber Crain

The ampoules have been stored in my filing cabinet so dark, relatively undisturbed and reasonably constant room temperature, obviously a bit warmer this summer

The thigh This location is preferable for self-administrated shots

Whether youre curious about a standard B12 shot or a skinny B12 shot (which typically includes additional metabolism-supporting ingredients), this simple injection can offer noticeable benefits, especially for those with low or borderline B12 levels