However, there are two patented active ingredients that stabilise the methylfolate and thus drastically increase bioavailability
The information below summarizes some, but not all, potential side effects, risks, and interactions
Limited research shows no dose adjustments needed
For patients who have difficulty absorbing B12 through the digestive tractsuch as those with pernicious anemia, gastrointestinal disorders (like Crohns disease or celiac disease), a history of gastric bypass surgery, or those with severe B12 deficiencyour providers often recommend intramuscular B12 injections
For some, especially women using hormone replacement therapy, symptoms may continue or even appear for the first time during menopause