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It may help improve exercise performance, enhance cardiac function, and reduce symptoms in individuals with heart-related conditions

10.1021/acscentsci.7b00028 195 ZilleM.KaruppagounderS

While positive airway pressure (PAP) is effective in keeping the upper airway open during sleep in individuals with moderate to severe OSA, about 30% to 50% of patients will discontinue PAP within the first year due to the cumbersome and uncomfortable nature of the device

doi: 10.1093/jn/133.7.2176

For example, arterialvenous blood sampling and isotope tracing experiments in pigs indicate that circulating citrate contributes to the tricarboxylic acid (TCA) cycle most prominently in the kidneys and to an extent that is similar to glutamine and lactate 22