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The first concerns evidence hierarchy: epidemiology and preclinical models can motivate a program but should not carry the confidence of a trial, and the gap between them deserves explicit caution before a Phase 3 commitment

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Target triazolium salt compounds were synthesized using a base-catalyzed click chemistry approach between azides and alkynes to make 1,5-diaryl-1,2,3-triazoles

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PLoS One 10 (7), e0132744