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As a mitigation strategy, if the test for period effect post unblinding was significant, then the statistical model for the primary outcome had to be recomputed only on the data from the first period of the trial (where period effect is taken out)as recommended by clinical practice ( The test indicated a significant period effect ( p 3.0.co;2-7, 40

How AOD-9604 Works AOD-9604 and Metabolic Health Research has shown that AOD-9604 can influence lipid metabolism in several ways

Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy

In a large cohort of RA patients, anti-TNF- therapy does not increase the risk of serious bacterial infections compared with MTX therapy

To confirm that the toxicity was due to depletion of GSH, we supplemented 2-AAPA treated zoospores with either GSH or GSSG (6)