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Hernndez-Rangel, A

Many cosmetic products do benefit from refrigeration to prolong efficacy, but it's not usually as critically short-lived as pure research-grade solutions

While this offers little hard information on flux through the various steps, it is consistent with glutathione making a relatively small contribution to ascorbate regeneration, all the more so if GR also has to maintain GSH oxidized by DHA-independent processes

Glutathione supplements tend to make the most sense for a specific set of people, rather than being a universal daily essential