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Front Pharmacol 12:693983 Zhu G, Deng Y, Feng J, Li Y, Chen L, Su Y, Ping A, Wang J, Xie F, Lv L (2024) "A preliminary study of thyroid hormones and thyroid ultrasonographic images in normal Chinese rhesus monkeys (Macaca mulatta)." Ziga D, Balasubramanian S, Mehmood KT, Al-Baldawi S, Salazar GZ (2024) "Hypothyroidism and cardiovascular disease: a review." Cureus 16(1)

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As a result, B12 supplements may help to prevent or reduce metformin-induced B12 deficiency and the development of Alzheimer's disease

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