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extended for analogs) GLP-3: Not well characterized Side Effects GLP-1: Nausea (common initially) Vomiting Diarrhea or constipation Reduced appetite Potential pancreatitis (rare) GLP-2: Generally well-tolerated Injection site reactions Abdominal pain or discomfort Nausea (less common than GLP-1) Fluid retention GLP-3: Unknown (no clinical use) Availability GLP-1: Widely available through prescription medications (semaglutide, liraglutide, etc.) and research peptides GLP-2: Available as teduglutide (Gattex/Revestive) by prescription

The goal of these detoxification pathways is to create molecules that the body can easily get rid of (urine, feces, sweat).[ref] CYP450 Genetic Variants: Genetic variants in CYP450 enzymes can significantly impact how an individual metabolizes various toxicants, medications, and substances produced within the body

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GLP-1 medications slow digestion, which changes how other oral drugs absorb

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