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The most significant factor is likely related to rapid weight loss and associated nutritional changes

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Direct Meds and the 2026 Insurance Coverage Loss Landscape Why 24 Million Americans Are Searching for GLP-1 Like Direct Meds Right Now Between 2025 and 2026 an estimated 24 million Americans lost insurance coverage for GLP-1 medications as major pharmacy benefit managers dropped GLP-1s from their formularies and employers restructured health benefits to manage pharmacy cost growth

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Any future settlements will depend on how the cases develop