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Side effects and safety considerations DSIP demonstrates a favorable safety profile in available research, but important considerations exist

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Red Flags: When to Contact Your Provider Immediately Monitor for signs of thyroid imbalance during semaglutide treatment: unexplained fatigue, sudden weight gain despite compliance, cold intolerance, or dry skin may signal hypothyroidism requiring a lower levothyroxine dose

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But as soon as they are opened and in use they can be stored at room temperature or refrigerated for up to 56 days