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It also has been described that -glutamylcysteine, the intermediate of GSH biosynthesis, is able to act as a Gpx1 cofactor in mitochondrial H 2 O 2 detoxification, mimicking the physiological properties of GSH (Quintana-Cabrera et al., 2012)
AMD is associated with progressive damage to macula, i.e., the central part of retina, and is a leading cause of loss of vision, and no effective therapy is available today
Imbalances in ion homeostasis and the degradation of antioxidant systems further impair lens function, accelerating cataract formation
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