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Bloodbrain barrier and gut barrier dysfunction in chronic kidney disease with a focus on circulating biomarkers and tight junction proteins

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After centrifugation, the plasma was separated and aliquoted into two cryovials

Although standard therapeutic modalities, including surgery, radiotherapy, chemotherapy, targeted therapy and immunotherapy, have improved, their clinical efficacy is often compromised by drug resistance, tumor microenvironment remodeling and immune evasion (2)

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