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The 30% body weight reduction in 28 days was achieved at doses optimized for the mouse model

was facing a GLP-1 apocalypse

The researchers found that P9 activates the ICAM-2 receptor on L-cells, triggering a signaling cascade that results in GLP-1 secretion

New or Worsening Food Intolerances: Sealing the tight junctions prevents large, undigested food proteins from entering the bloodstream, which reduces the immune system's hyper-reactive antibody response to previously tolerated foods