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The nature of antioxidant defense mechanisms: a lesson from transgenic studies

Intestinal tissue of male Wistar rats fed ad libitum but fasted for 24 h prior to euthanasia showed a 2.5-fold increase in the oxidation state of the pyruvate/lactate between 4 and 24 months of age (Papila et al., 2024)

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This enhanced bioavailability means more of the antioxidant reaches your cells and your liver, where it can actively support glucose metabolism and oxidative stress reduction