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Their use is currently contraindicated for patients with atypical anorexia nervosa, bulimia nervosa, or subthreshold bulimia nervosa, as GLP-1RAs could worsen the restrictive eating behaviors common in these conditions

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Protocol: Creatine: 5g daily (no loading) Protein: 1.4-1.6g per kg body weight Resistance training: 3x per week, compound movements, moderate to heavy loads Tracking: Waist circumference, strength logs, monthly progress photos Duration: Continue creatine throughout entire tirzepatide treatment and beyond This protocol maximizes the muscle-sparing effect of creatine while tirzepatide handles the fat loss side

Frequency varies by need, some benefit from weekly injections, others monthly.

Heidrun Karlic, Alfred Lohninger, Supplementation of l-carnitine in athletes: does it make sense?, Nutrition, Volume 20, Issues 78, 2004, Pages 709-715, ISSN 0899-9007, 6