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While agonism has a significant immunoregulatory and immunosuppressive function, the antagonism of [the] GLP-1 receptor is immunostimulatory, Paolo Fiorina, MD, PhD, research associate in the Department of Pediatrics Research in the Division of Nephrology Research at Boston Childrens Hospital and senior author of this study explained to Medical News Today

In addition, the three peptides can also regulate the function of the immune system and enhance the body's anti-tumor immunity

Additionally, the FOXO4-p53 interaction contributes to the maintenance of senescent cells by activating the transcription of their common target gene, p21cip1, which suppresses apoptosis 36