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This hypermetabolic state paradoxically makes weight loss difficult despite increased calorie burning, because the body's regulatory systems become dysregulated

Last reviewed: July 17, 2026 Last updated: July 17, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

The active ingredient dissolves completely once dispersed

These drugs have shown efficacy beyond glycaemic regulation, including significant weight loss, cardiovascular protection, and possible advantages for renal function