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Metsera is exploring a range of weekly doses for its Phase 2b trials in obesity (with or without T2D separately), and looks to find the optimized weekly dose for both efficacy/tolerability

Tolhurst G, Heffron H, Lam YS, Parker HE, Habib AM, Diakogiannaki E, Cameron J, Grosse J, Reimann F, and Gribble FM

Under dietetic guidance, an intake of approximately 1.0 to 1.2 grams per kilogram of body weight daily may be appropriate, particularly for older adults or those losing weight

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