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Furthermore, the low consumption of vegetables and fruits causes a lack of exogenous antioxidants, while an excessive intake of animal proteins (mainly red and processed meat) and fats has been associated with increased oxidants, increasing the risk of immune-mediated disorders, including autoimmune thyroid diseases [186, 187]

Science 362 , 956960 (2018)

These observations suggested that induction of HO-1 ameliorates detrimental inflammation in a variety of diseases, which also exhibited the preventive therapeutic approaches and management strategies of HO-1 expression for diabetes

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Refractory Systemic Lupus Erythematosus: Identification and Pharmacological Management