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Rd10 mice possess a PDE6 mutation that initially leads to rod degeneration, followed by progressive cone loss [33]

From gestational chronodisruption to noncommunicable diseases: Pathophysiological mechanisms of programming of adult diseases, and the potential therapeutic role of melatonin

While IBS causes discomfort and irregularity, it does not damage intestinal tissue

These pathogenic processes ultimately result in massive -cell loss and absolute insulin deficiency, thereby inducing dysregulation of glucose homeostasis (164)