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Unlike tirzepatide, which activates both GLP-1 and GIP receptors, MariTide is a GIPR antagonist antibody/GLP-1R peptide agonist conjugate which means that it activates GLP-1 receptors while blocking GIP responses

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Past studies looking at the safety of the thymosin alpha-1 peptide found the most common side effects were local irritation, discomfort, or redness at the injection site