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In 2017, subcutaneous semaglutide was the most effective of all GLP-1 medications for lowering A1C: at 40 weeks, patients had a -1.5% A1C reduction using subcutaneous semaglutide vs
calculated as weight in kilograms divided by height in meters squared) of 27 or higher, with baseline weight measurement available, regular interactions with the health care system in the previous year, and a prescription for a GLP-1 RA in the preceding 2 months were included
During the past years, the intestine and in particular, intestinal epithelial cells (IEC) are more and more recognized as key players in maintaining metabolic and immune homeostasis