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Immunostaining revealed mixed cell populations with many undifferentiated hPSCs and mesoderm cells, and DE markers SOX17 and FOXA2 were expressed at lower levels compared to the Activin A-based control (CA)

Despite observing expected processes associated with GLP1R activity, like influence on T2D, hyper- and hypoglycaemia and obesity we observed a plethora of other processes and pathways which could be considered a side effect of GLP1R targeted therapy