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Understanding its mechanism is key to discussing its potential co-administration with other medications

Preserving and rebuilding lean muscle is one of the most important predictors of long-term metabolic health

For decades, spironolactone has been one of the main drugs targeting this pathway

doi: 10.3389/fmed.2020.00047 239

Studies have found that GLP-1R is widely distributed on pancreatic and other tissues and has multiple biological effects, such as reducing neuroinflammation, promoting nerve growth, improving heart function, suppressing appetite, delaying gastric emptying, regulating blood lipid metabolism and reducing fat deposition