Wilhelm AJ, Zabalawi M, Grayson JM, Weant AE, Major AS, Owen J, Bharadwaj M, Walzem R, Chan L, Oka K, Thomas MJ, Sorci-Thomas MG
Check the fat content in your meals
Preclinical studies across diverse neurodegenerative conditions consistently demonstrate neuroprotective effects of GLP-1RAs, including reduced protein aggregation, enhanced autophagy, improved mitochondrial function, suppression of neuroinflammation, and preservation of synaptic integrity
It has been suggested that LPS plays an essential role in the onset of obesity and T2D development (74) showed that deletion of the TLR4 and co-receptor CD14, which are involved in LPS signaling (60, 61), did not prevent diet-induced obesity in mice, suggesting that obesity may develop independent of LPS and metabolic endotoxemia
Carbohydrate timing is equally important: post-workout carbohydrate intake (50100g high-glycemic) replenishes muscle glycogen and stimulates insulin release, which synergizes with IGF-1 to drive amino acid transport into muscle cells
