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One 2024 study at the Smell and Taste Center at the University of Pennsylvania (source) found evidence of GLP1 agonists significantly depressing the perception of all five basic taste qualities. Interestingly, while all participants in the study experienced a slight decline in their sense of smell, it was not considered statistically significant suggesting that olfactory changes may be more individualised, or more complex to detect in standardised tests

Timing your GLP-1 injection around meals One of the most common questions researchers ask is whether they should time their injection relative to meals

The clinical answer is that most patients lose between 2 and 5 pounds in the first four weeks, and much of that is water weight and early appetite reduction, not fat loss

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As you shed pounds, your metabolism naturally adapts to your new body weight, causing the weight loss to slow down