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For patients who have neurofibrosarcomas in an extremity, if the tumor is vascularized (has its own blood supply) and has many nerves going through it and/or around it, amputation of the extremity may be necessary

THE EXECUTION With the concept locked, the work shifted from high-level narrative to deciding exactly what we would say and how we would bring it to lifefrom art direction and the script, to director choice and production

For clients who experience this, its worth looking deeper

Do not wait for routine labs Severe daytime sedation, confusion, breathing pauses during sleep, or worsening mood symptoms need clinical review

Genetic variants in carnitine-related genes (SLC22A5, CPT1, CPT2) can cause disorders that affect energy production, causing issues from mild fatigue to severe dysfunction