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In research, it functions as a melanocortin receptor agonist derived from the C-terminal region of -MSH

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Effects on laboratory mammals and in vitro test systems 1.1.7

However, several factors related to the patients characteristics, glucocorticoid course of therapy, and biochemical testing could be used to estimate the recovery of the HPAA and help clinicians with their approach to patients with GIAI

Inflammation may itself cause demyelination, as in MS, in which leptomeningeal immune cell infiltration and compartmentalized inflammation within the subarachnoid space are tightly associated with the development of cortical lesions (Choi et al., 2018)