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Age-Related Sleep Decline Melatonin production declines naturally with age older adults produce significantly less melatonin, which contributes to the lighter, more fragmented sleep patterns that characterize aging

doi:10.1126/science.aam9756

Hamilton KL, Butt AG

3 rd Yarrowia lipolytica international meeting: cell biology and biotechnology of a nonconventional yeast, 20 July 2002, University of Technology, Dresden, Germany

In this work, we construct a multiple hydrogen-bond crosslinked hydrogel loaded with tannic acid and Kartogenin by polyaddition reaction as a cell-free scaffold for in vivo cartilage regeneration, which features ultra-durable mechanical properties and stage-dependent drug release behavior