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So that was the direction of the pharmacologic industry very very early on, and that started in 2005

In the fish, creatine plus phosphocreatine concentrations in skeletal muscle were 1315, 1316, and 112125 times those in the proximal intestine, kidneys, and liver, respectively, whereas GSH concentrations in the liver were 3.23.5, 5.36.6, and 911 times those in the proximal intestine, kidneys, and skeletal muscle, respectively

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In addition, propionyl-L-carnitine was found to improve lactate clearance by 43% and increase stroke volume by 8% in patients with ischemia