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Immunopharmacol Immunotoxicol 1991;13:135-46 60 -De Simone C

Many patients at higher doses switch to a 30 mg/mL concentration specifically to avoid this issue

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This is neurochemistry

Conclusion The glucagon-like peptide-1 receptor agonist ROSE-010 has been shown in studies to be beneficial in lowering the severity of pain in individuals with IBS