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[PubMed: 1645339] 782

Vitamin B12 is a vital component in ensuring we function properly in our day to day lives

Also, hyperglycemia causes increased glucose and sodium reabsorption at the proximal tubule reducing the sodium delivery to the macula densa

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These authors used the obese Otsuka Long Evans Tokushima Fatty (OLETF) rat model, in which rats become hyperphagic due to knockout of the cholecystokinin receptor, which senses cholecystokinin that is released from I cells in the small intestine and regulates food intake and satiety through neuronal feedback to the brain (159)