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In agreement with our immunoblotting analysis, we observed an induction of CHAC1 under cystine starvation in CHAC1 expressing H1299 cells but not those subject to CRISPR/Cas9-mediated CHAC1 knockout 48 , indicating antibody specificity (Supplementary Fig

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People taking GLP-1 medications who experience significant mood changes, increased irritability, or behavioral changes should report them to their prescribing clinician, as these effects would be relevant to ongoing safety monitoring

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