However, we did observe that ML226 drove a memory T cell phenotype, as after 11 days of treatment, there was an increase in the CCR7 high CD45RO high central memory T cell population (T CM ), and a corresponding decrease in the CCR7 low CD45RO high effector memory T cell population (T EM
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In cultured hippocampal neurons, depletion of Ogt disrupts neuronal maturation via the Wnt/-catenin signaling pathway, manifesting as reduced dendritic numbers and lengths, as well as immature spine development [59]
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