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Serum B12 alone misses up to 50% of functionally deficient patients because it measures total B12 in the blood, including inactive forms your cells cant use [1]

Ippolito, L., Giannoni, E., Chiarugi, P

Reserpine as a monoamine-depleting agent that blocks the transport of these neurotransmitters into their vesicles by inhibiting the activity of vesicular monoamine transporter (VMAT) can contribute to an increase in oxidative stress in nerve cells and exhaustion of antioxidant molecules such as GSH

Koenig and Preston Sutton analyzed Raman spectra of poly-L-lysine in both aqueous solution and solid state, and showed that although this homopolymer behaves as a random coil in aqueous solutions, it folds into -helical structure in solid state (Koenig and Sutton, 1970)