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Conclusions This study demonstrates that a single administration of genome editing can achieve sustained therapeutic peptide secretion, providing a potential strategy for treating complex diseases without defined genetic causes

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doi: 10.2174/1389450116666150722141418 [DOI] [PubMed] [Google Scholar] 165

While a similar study in pigs did not confirm these findings, the follow-up period was only 3 days, which may have been insufficient time to reveal a positive effect (223)