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3739 While it is encouraging that the weight loss achieved with GLP-1/GIPGLP-1 receptor agonists approaches levels typically seen after bariatric procedures such as gastric bypass or sleeve gastrectomy, the rapid regain of a significant portion of the lost weight after treatment discontinuation, accompanied by a reduction in lean body mass, raises new clinical concerns

Summary Keywords chronic fatigue syndrome (CFS), inflammation, neuro-immune, oxidative and nitrosative stress, myalgic encephalomyelitis, antioxidants, bacterial translocation Citation Maes M, Kubera M and Kotaska M (2022) Aberrations in the Cross-Talks Among Redox, Nuclear Factor-B, and Wnt/-Catenin Pathway Signaling Underpin Myalgic Encephalomyelitis and Chronic Fatigue Syndrome

By attacking the sombretropic control system from two separate and vital pathways, researchers observe a GH peak that is far superior to those achieved by single secretagogues

Kehler, J

Hsueh, Y