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Gallbladder disease may necessitate surgical removal of the gallbladder, a procedure that carries its own risks and recovery period

Together, these studies show that inhibition of lipogenic pathways protects from MASLD in multiple models with decreased levels of lipogenic genes, and that GSH depletion through Chac1 overexpression recapitulates similar protective effects by broadly downregulating lipogenic genes

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Its use is only permitted within formally approved clinical trials