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However, it is important to note that GLP-1 medications are meant to supplement a balanced diet and healthy lifestyle, not replace it

These findingsoriginating from landmark trials such as EMPA-REG OUTCOME, LEADER, and SUSTAIN-6have led to substantial revisions in international guidelines from the European Society of Cardiology, American College of Cardiology, and American Heart Association, which now recommend the use of SGLT2i or GLP-1 RAs, often in conjunction with metformin

Combining a GLP-1 with insulin or certain other diabetes drugs can push blood sugar too low, which is exactly the kind of thing a doctor adjusts for before you take a first dose

Endnote @nbcnewsThe World Health Organization is now recommending GLP-1 drugs as a tool to manage obesity in adults, alongside healthy dieting and physical activity

The overall effect tends to make people look older than they are