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Therefore, further screening with ApoB to measure particle number is not so much about diagnosing people but really about finding that subset of patients who might need more medication and more aggressive treatment to lower their cholesterol even further

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GLP-1 receptor signaling in astrocytes regulates fatty acid oxidation, mitochondrial integrity, and function

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Overall, this work highlights the clinical potential of GC-PDCOs to guide personalized therapy, predict treatment response, and uncover mechanisms of resistancebridging the gap between bench research and bedside decision-making in precision oncology