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Many patients begin to notice appetite changes within the first 12 weeks, with more visible progress developing over the following months

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Regular HbA1c testing (typically every three months until stable, then potentially every six months), self-monitoring of blood glucose as directed, and periodic weight checks allow you and your healthcare provider to assess treatment response

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33 In a phase 2 open-label study, NGM282 improved the histological features of MASH within 12 weeks, demonstrating significant reductions in NAS and fibrosis scores, along with improvements in noninvasive imaging and serum markers