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) for the test groups, sodium valproate (300 mg/kg

Future studies should address this gap to provide further clarity on these effects

Recent developments in automated sampling of blood (159) and tissue interstitial fluid via microdialysis (160) have also uncovered the ultradian rhythms in plasma ACTH which correlate well with plasma and tissue steroid (cortisol and cortisone) concentrations, indicating that the ultradian rhythms in blood ACTH and cortisol/cortisone translate well to tissue exposure to these steroids

doi:10.1186/s12958-018-0437-8

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